Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ADH5 | P11766 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19244631 | 0.88 | CA12 (0.48) | HPGDSALKBH2MAPTMEN1KMT2A | |
| SCHEMBL16144601 | 0.86 | TPMT (0.50) | HPGDSALKBH2MAPTMEN1KMT2A | |
| SCHEMBL6758328 | 0.86 | SMN1; SMN2 (0.50) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL18672145 | 0.85 | ALDH1A1 (0.54) | HPGDSALKBH2KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL458419 | 0.84 | NPC1 (0.46) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL182018 | 0.83 | KDM4E (0.48) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL181897 | 0.83 | KMO (0.51) | HPGDSALKBH2MAPTMEN1KMT2A | |
| SCHEMBL181765 | 0.82 | EGLN1 (0.48) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL182399 | 0.82 | KMO (0.46) | SMN1; SMN2RAB9ANPC1HSP90AA1NFKB1 | |
| SCHEMBL2396469 | 0.81 | CYP11B1 (0.44) | MAPTMEN1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| EP-2247603-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-09-28 | — | — | EP | disclosed |
| US-9018363-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-28 | — | — | US | disclosed |
| US-9018363-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-28 | — | — | US | disclosed |
| US-9006468-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-9006468-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-8927729-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-8674109-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-20120190543-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120172218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DDT, ACHE, NANP | HPGDS 1679/4885ALKBH2 2891/4885MAPT 2297/4885 |
| US-20120172218-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | HPGDS 3031/4885ALKBH2 1842/4885MAPT 3378/4885 |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | HPGDS 3031/4885ALKBH2 1842/4885MAPT 3378/4885 |
| US-20120190543-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, AADAC | HPGDS 4535/4885ALKBH2 1117/4885MAPT 3486/4885 |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | HPGDS 3031/4885ALKBH2 1842/4885MAPT 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.