Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985031 | 0.87 | KCNJ1 (0.40) | KCNJ1PTGS2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL18672145 | 0.85 | ALDH1A1 (0.54) | KCNJ1ALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL19244927 | 0.84 | KCNJ1 (0.45) | KCNJ1PTGS2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL19244630 | 0.84 | ALDH5A1 (0.48) | KCNJ1ALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL4549492 | 0.84 | CYP2A6 (0.48) | KCNJ1ALDH1A1KDM4EMAPK1POLB | |
| SCHEMBL458419 | 0.84 | NPC1 (0.46) | PTGS2ALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL2396469 | 0.81 | CYP11B1 (0.44) | ALDH1A1KDM4EMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL16030407 | 0.81 | KCNJ1 (0.42) | KCNJ1PTGS2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL19244926 | 0.81 | KCNJ1 (0.42) | KCNJ1PTGS2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL4549490 | 0.81 | HPGDS (0.50) | ALDH1A1KDM4EPOLBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | KCNJ1 1307/4885PTGS2 910/4885ALDH1A1 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.