Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451016 | 0.81 | MEN1 (0.44) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL16808779 | 0.78 | CCNB2 (0.35) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL2237097 | 0.78 | TRPA1 (0.37) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL2202537 | 0.78 | VHL (0.38) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL11941058 | 0.78 | ALDH1A1 (0.43) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL1680897 | 0.78 | HRH3 (0.42) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL7473813 | 0.78 | CCNB2 (0.35) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL6517744 | 0.76 | FOLH1 (0.38) | IDO1MEN1KMT2ACYP2C19HTT | |
| SCHEMBL23703708 | 0.75 | TDP1 (0.41) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL8803609 | 0.75 | CA2 (0.45) | CCNB2CDK1CCNB1GSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603951-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-03-28 | — | — | US | disclosed |