Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23703708 | 0.83 | TDP1 (0.41) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL9451016 | 0.81 | MEN1 (0.44) | TSHRCCNB2CDK1CCNB1GSK3B | |
| SCHEMBL15074365 | 0.80 | MEN1 (0.33) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL18672255 | 0.78 | IDO1 (0.39) | ALDH1A1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL2202537 | 0.78 | VHL (0.38) | TSHRCCNB2CDK1CCNB1GSK3B | |
| SCHEMBL16808779 | 0.78 | CCNB2 (0.35) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL1680897 | 0.78 | HRH3 (0.42) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL11941058 | 0.78 | ALDH1A1 (0.43) | ALDH1A1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL7473813 | 0.78 | CCNB2 (0.35) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL8022584 | 0.76 | ALDH1A1 (0.37) | TRPA1ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383867-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2021-04-14 | — | — | EP | disclosed |
| EP-3383867-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2021-04-14 | — | — | EP | disclosed |
| EP-3269741-B1 | METHOD FOR MAKING A FUNCTIONALIZED ELASTOMER VIA ALLYLBORATION | GOODYEAR TIRE & RUBBER (US) | 2019-05-15 | — | — | EP | disclosed |
| EP-3269745-B1 | FUNCTIONALIZED ELASTOMER VIA ALLYLBORATION | GOODYEAR TIRE & RUBBER (US) | 2019-04-03 | — | — | EP | disclosed |
| EP-3383867-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.A. (IT) | 2018-10-10 | — | — | EP | disclosed |
| US-9932338-B2 | Compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-04-03 | — | — | US | disclosed |
| US-9932338-B2 | Compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-04-03 | — | — | US | disclosed |
| US-9932338-B2 | Compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-04-03 | — | — | US | disclosed |
| EP-3269745-A1 | FUNCTIONALIZED ELASTOMER VIA ALLYLBORATION | The Goodyear Tire & Rubber Company (US) | 2018-01-17 | — | — | EP | disclosed |
| EP-3269741-A1 | METHOD FOR MAKING A FUNCTIONALIZED ELASTOMER VIA ALLYLBORATION | The Goodyear Tire & Rubber Company (US) | 2018-01-17 | — | — | EP | disclosed |
| WO-2016050210-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | 厦门赛诺邦格生物科技有限公司 | 2016-04-07 | — | — | WO | disclosed |
| EP-2662353-A2 | Antibacterial agents | Achaogen, Inc. (US) | 2013-11-13 | — | — | EP | disclosed |
| WO-2011092028-A1 | NANOPARTICLES AND NANOINK | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-08-04 | — | — | WO | disclosed |
| WO-2011092028-A1 | NANOPARTICLES AND NANOINK | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-08-04 | — | — | WO | disclosed |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
| WO-2008154642-A2 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2008-12-18 | — | — | WO | disclosed |
| US-4447428-A | BRONCHODILATOR, ANTICOAGULANTS | GLAXO GROUP LIMITED (GB) | 1984-05-08 | — | — | US | disclosed |
| US-4409213-A | B-SIDE CHAIN ATTACHED THRU AMINO GROUP; BRONCHODILATORS, ANTICOAGUANT | GLAXO GROUP LIMITED (GB) | 1983-10-11 | — | — | US | disclosed |
| US-4265891-A | PROSTAGLANDINS, BRONCHODILATORS, PLATELET AGGREGATION INHIBITORS | GLAXO GROUP LIMITED (GB) | 1981-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | TRPA1 3491/4885ALDH1A1 687/4885TSHR 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.