Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18674468 | 0.95 | PPARG (0.46) | PPARGPPARAOPRK1OPRM1OPRD1 | |
| SCHEMBL18677874 | 0.89 | PPARG (0.43) | PPARGPPARAOPRK1OPRM1OPRD1 | |
| SCHEMBL18674511 | 0.86 | OPRK1 (0.41) | PPARGPPARACA12CA1CA2 | |
| SCHEMBL18674466 | 0.81 | PPARG (0.41) | PPARGPPARAOPRK1OPRM1OPRD1 | |
| SCHEMBL11303647 | 0.80 | TDP1 (0.38) | DRD3L3MBTL1KDM4ELMNACHRM2 | |
| SCHEMBL11306734 | 0.78 | TDP1 (0.37) | PPARGPPARADRD3L3MBTL1KDM4E | |
| SCHEMBL14496261 | 0.75 | TDP1 (0.43) | KDM4EMEN1LMNAKMT2A | |
| SCHEMBL13939569 | 0.75 | FFAR1 (0.41) | PPARGPPARAL3MBTL1 | |
| SCHEMBL5337605 | 0.73 | LMNA (0.55) | CA12CA1CA2L3MBTL1ACHE | |
| SCHEMBL2443821 | 0.73 | KEAP1 (0.54) | CA12CA1CA2OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170089913-A1 | NEW CHROMOPHORIC STRUCTURES FOR LANTHANIDE CHELATES | RADIOMETER TURKU OY (FI) | 2017-03-30 | — | — | US | disclosed |