Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17069208 | 0.80 | ALOX15 (0.33) | ALOX15ALOX12GABRA1GABRB2PTGS2 | |
| SCHEMBL18682193 | 0.77 | GRIN2D (0.35) | — | |
| SCHEMBL8723828 | 0.76 | — | — | |
| SCHEMBL17069232 | 0.74 | PDE2A (0.40) | GABRB2PTGS2PTGS1 | |
| SCHEMBL9879079 | 0.74 | — | — | |
| SCHEMBL8097016 | 0.73 | CYP3A4 (0.35) | ALOX15ALOX12GABRA1GABRB2 | |
| SCHEMBL17069250 | 0.73 | DPP4 (0.46) | ALOX15ALOX12GABRA1GABRB2 | |
| SCHEMBL8724897 | 0.72 | MEN1 (0.31) | — | |
| SCHEMBL17069253 | 0.72 | PNMT (0.39) | ALOX15ALOX12GABRA1GABRB2PTGS2 | |
| SCHEMBL23434791 | 0.72 | CDK2 (0.33) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9694002-B2 | Substituted benzamides and methods of use thereof | GENENTECH, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20170087136-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170087136-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | C1R, SRR, PNISR | ALOX15 4410/4885ALOX12 4241/4885GABRA1 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.