SCHEMBL24744482

SCHEMBL24744482

CCCN1CCC(NC(=O)CC)CC1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.62
EPHX1 P07099 2/20 0.55
EPHX2 P34913 2/20 0.55
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
HRH3 Q9Y5N1 1/20 0.49
KDM4E B2RXH2 2/20 0.48
UBE2M P61081 1/20 0.48
DCUN1D1 Q96GG9 1/20 0.48
CHRM1 P11229 5/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
CCR8 P51685 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23711916 0.88 L3MBTL1 (0.50) L3MBTL1EPHX1EPHX2KMT2AHRH3
SCHEMBL13191363 0.85 EPHX2 (0.53) L3MBTL1EPHX1EPHX2MEN1KMT2A
SCHEMBL26095596 0.85 L3MBTL1 (0.48) L3MBTL1HRH3CHRM1ALDH1A1SIGMAR1
SCHEMBL13136091 0.84 EPHX1 (0.56) L3MBTL1EPHX1EPHX2MEN1KMT2A
SCHEMBL16200513 0.83 HRH3 (0.51) L3MBTL1MEN1KMT2AHRH3KDM4E
SCHEMBL10265277 0.83 SIGMAR1 (0.49) L3MBTL1EPHX2HRH3CHRM1ALDH1A1
SCHEMBL17513083 0.82 SMN1; SMN2 (0.57) L3MBTL1EPHX2HRH3CHRM1SMN1; SMN2
SCHEMBL28754536 0.81 HRH3 (0.58) L3MBTL1EPHX1EPHX2HRH3CHRM1
SCHEMBL23986333 0.81 EPHX2 (0.61) L3MBTL1EPHX1EPHX2MEN1KMT2A
SCHEMBL18676271 0.81 EPHX1 (0.54) L3MBTL1EPHX1EPHX2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022255888-A1 TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN CAPTOR THERAPEUTICS S.A. (PL) 2022-12-08 WO disclosed
WO-2022253713-A1 TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN CAPTOR THERAPEUTICS S.A. (PL) 2022-12-08 WO disclosed