Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700614 | 0.86 | LMNA (0.50) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL1873173 | 0.82 | MAPT (0.39) | LMNAMEN1KMT2AALDH1A1HCAR3 | |
| SCHEMBL24283552 | 0.78 | MAPT (0.55) | MEN1KMT2APOLBALDH1A1HCAR3 | |
| SCHEMBL28153189 | 0.72 | MAPT (0.47) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL1873077 | 0.72 | KMT2A (0.47) | MEN1KMT2APOLBALDH1A1HCAR3 | |
| SCHEMBL1700370 | 0.69 | MAPT (0.46) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL1700636 | 0.69 | KMT2A (0.52) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL21496893 | 0.68 | HPGD (0.46) | MEN1KMT2AALDH1A1HCAR3MAPT | |
| SCHEMBL3762305 | 0.68 | HPGD (0.58) | LMNAMEN1KMT2AALDH1A1HCAR3 | |
| SCHEMBL28151931 | 0.67 | ALOX12 (0.43) | LMNAMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138588-A9 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-05-05 | — | — | WO | disclosed |