Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13116576 | 0.83 | MAPK1 (0.50) | NAMPTMAPK1HPGDMEN1CYP1A2 | |
| SCHEMBL13634518 | 0.80 | SIRT3 (0.50) | NAMPTMAPK1HPGDMEN1CYP1A2 | |
| SCHEMBL17438594 | 0.77 | MAPK1 (0.48) | NAMPTMAPK1HPGDMEN1CYP1A2 | |
| SCHEMBL14875446 | 0.77 | AOC1 (0.49) | NAMPTMAPTBRAFHTTPDCD1 | |
| SCHEMBL17438584 | 0.76 | MAPK1 (0.47) | NAMPTMAPK1HPGDMAPTMEN1 | |
| SCHEMBL13162041 | 0.72 | ALDH1A1 (0.54) | HPGDKMT2ATDP1TP53ALDH1A1 | |
| SCHEMBL8488280 | 0.71 | NAMPT (0.64) | NAMPTHPGDMAPTCYP1A2CYP3A4 | |
| SCHEMBL1116738 | 0.70 | KMT2A (0.76) | MAPTMEN1CYP1A2CYP3A4KMT2A | |
| SCHEMBL29634495 | 0.70 | KMT2A (0.76) | MAPTMEN1CYP1A2CYP3A4KMT2A | |
| SCHEMBL28183358 | 0.70 | MAPK1 (0.56) | MAPK1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088876-A1 | Assays, Methods and Means | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088876-A1 | Assays, Methods and Means | EGLN3, EGLN2, P4HA1 | NAMPT 2732/4885MAPK1 3073/4885HPGD 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.