Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18680417 | 0.86 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1EEDRBBP4SUZ12 | |
| SCHEMBL18680410 | 0.73 | ALDH1A1 (0.33) | ALDH1A1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL12249889 | 0.66 | — | — | |
| SCHEMBL18680419 | 0.66 | ACHE (0.35) | ALDH1A1CYP3A4TSHRCYP2C19TP53 | |
| SCHEMBL5888474 | 0.65 | LMNA (0.35) | ALDH1A1L3MBTL1EEDRBBP4SUZ12 | |
| SCHEMBL12248160 | 0.65 | KCNA5 (0.46) | ALDH1A1CYP3A4TSHRCYP2C19KCNA5 | |
| Hydrochloric Acid SCHEMBL5888277 | 0.64 | LMNA (0.34) | ALDH1A1L3MBTL1EEDRBBP4SUZ12 | |
| SCHEMBL22711434 | 0.61 | DPP4 (0.47) | ALDH1A1CYP3A4TSHRCYP2C19KCNA5 | |
| SCHEMBL16852689 | 0.61 | KCNA5 (0.42) | ALDH1A1L3MBTL1CYP3A4TSHRCYP2C19 | |
| SCHEMBL28209343 | 0.61 | EED (0.43) | ALDH1A1L3MBTL1EEDRBBP4SUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938240-B2 | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX INC. (CA) | 2018-04-10 | — | — | US | disclosed |
| US-20170088518-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | THE BANK OF NOVA SCOTIA (CA) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088518-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | FH, FECH, FPGS | ALDH1A1 537/4885L3MBTL1 2228/4885EED 2683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.