Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6614694 | 0.80 | DPEP1 (0.38) | DPEP1 | |
| SCHEMBL23315549 | 0.76 | CTSL (0.39) | — | |
| SCHEMBL8508772 | 0.73 | CYP1A2 (0.44) | — | |
| SCHEMBL6542877 | 0.72 | SLC6A2 (0.39) | SLC6A3KCNH2 | |
| SCHEMBL5455820 | 0.72 | SLC6A2 (0.39) | SLC6A3KCNH2 | |
| Ammonia Solution, Strong SCHEMBL27594272 | 0.70 | SLC6A2 (0.38) | SLC6A3KCNH2 | |
| SCHEMBL12473621 | 0.70 | SLC6A2 (0.41) | SLC6A3 | |
| SCHEMBL8256061 | 0.68 | IDO1 (0.44) | SLC6A3KCNH2MAOAMAOB | |
| SCHEMBL349726 | 0.68 | IDO1 (0.44) | SLC6A3KCNH2MAOAMAOB | |
| SCHEMBL12052163 | 0.68 | IDO1 (0.44) | SLC6A3KCNH2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914702-B2 | Amine derivatives as potassium channel blockers | BIONOMICS LIMITED (AU) | 2018-03-13 | — | — | US | disclosed |
| US-20170088519-A1 | AMINE DERIVATIVES AS POTASSIUM CHANNEL BLOCKERS | BIONOMICS, LTD (AU) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088519-A1 | AMINE DERIVATIVES AS POTASSIUM CHANNEL BLOCKERS | KCNA3, KCNH3, KCNK3 | SLC6A3 296/4885KCNH2 4/4885DPEP1 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.