SCHEMBL23315549

SCHEMBL23315549

CC(CC1CCCC1)c1ccc(F)cc1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.39
KLK7 P49862 1/20 0.38
CTSS P25774 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29706730 0.80 SLC6A2 (0.54)
SCHEMBL3587637 0.79 GAA (0.50)
SCHEMBL21227006 0.77 GCK (0.36)
SCHEMBL31388237 0.76 PDE4A (0.44)
SCHEMBL18685331 0.76 SLC6A3 (0.36)
SCHEMBL21226956 0.75 MEN1 (0.46)
SCHEMBL21227005 0.75 GCK (0.47)
SCHEMBL8508772 0.74 CYP1A2 (0.44)
SCHEMBL6614694 0.74 DPEP1 (0.38)
SCHEMBL21226989 0.74 ALDH1A1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3620454-B1 CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2021-05-05 EP disclosed