Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127386 | 0.93 | CSNK2A1 (0.41) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL18686168 | 0.93 | CSNK2A1 (0.43) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL18686156 | 0.87 | MPO (0.39) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL18686159 | 0.86 | CSNK2A1 (0.42) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL2122009 | 0.86 | PRKCQ (0.42) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL2125521 | 0.86 | PRKCQ (0.42) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL2125564 | 0.86 | PRKCQ (0.42) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL2126389 | 0.85 | ALDH1A1 (0.47) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL2122304 | 0.85 | CSNK2A1 (0.43) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL2123521 | 0.85 | PRKCQ (0.52) | CSNK2A1PRKCQEGFRERBB2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443123-B1 | SMALL MOLECULE INHIBITORS OF SPLEEN TYROSINE KINASE (SYK) | RIGEL PHARMACEUTICALS INC (US) | 2017-04-05 | — | — | EP | claimed |