Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | ESR1 | P03372 | 6/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | PGR | P06401 | 2/20 | 0.77 |
| ▸ | AR | P10275 | 2/20 | 0.77 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.77 |
| ▸ | ATM | Q13315 | 2/20 | 0.77 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.77 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.77 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.77 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.77 |
| ▸ | STS | P08842 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Estradiol Methyl Ether SCHEMBL12593628 | 1.00 | HSD17B10 (1.00) | HSD17B10LMNAESR1SMN1; SMN2PGR | |
| Estradiol Methyl Ether SCHEMBL14499084 | 1.00 | HSD17B10 (1.00) | HSD17B10LMNAESR1SMN1; SMN2PGR | |
| Estradiol Methyl Ether SCHEMBL8998255 | 1.00 | HSD17B10 (1.00) | HSD17B10LMNAESR1SMN1; SMN2PGR | |
| Estradiol Methyl Ether SCHEMBL15263441 | 1.00 | HSD17B10 (1.00) | HSD17B10LMNAESR1SMN1; SMN2PGR | |
| Estradiol Methyl Ether SCHEMBL547265 | 1.00 | HSD17B10 (1.00) | HSD17B10LMNAESR1SMN1; SMN2PGR | |
| Estradiol Methyl Ether SCHEMBL6464173 | 1.00 | HSD17B10 (1.00) | HSD17B10LMNAESR1SMN1; SMN2PGR | |
| Estradiol Methyl Ether SCHEMBL23645792 | 1.00 | HSD17B10 (1.00) | HSD17B10LMNAESR1SMN1; SMN2PGR | |
| Estradiol Methyl Ether SCHEMBL9558220 | 1.00 | HSD17B10 (1.00) | HSD17B10LMNAESR1SMN1; SMN2PGR | |
| Estradiol Methyl Ether SCHEMBL4750578 | 1.00 | HSD17B10 (1.00) | HSD17B10LMNAESR1SMN1; SMN2PGR | |
| SCHEMBL980768 | 0.92 | LMNA (0.85) | HSD17B10LMNAESR1SMN1; SMN2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019008441-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2019-01-10 | — | — | WO | disclosed |
| US-20170088563-A1 | BASE-CATALYZED SILYLATION OF TERMINAL ALKYNE C-H BONDS | NATIONAL SCIENCE FOUNDATION | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088563-A1 | BASE-CATALYZED SILYLATION OF TERMINAL ALKYNE C-H BONDS | ALKBH3, CA3, ALKBH2 | HSD17B10 663/4885LMNA 527/4885ESR1 2796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.