SCHEMBL18691843

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12640087	0.84	STAT3 (0.75)	STAT3ALDH1A1KMT2AMEN1CDC25B
	Napabucasin SCHEMBL1883845	0.84	STAT3 (1.00)	STAT3ALDH1A1KMT2AMEN1CDC25B
	Napabucasin SCHEMBL29349770	0.84	STAT3 (1.00)	STAT3ALDH1A1KMT2AMEN1CDC25B
	SCHEMBL12640086	0.83	STAT3 (0.73)	STAT3ALDH1A1KMT2AMEN1CDC25B
	SCHEMBL12494612	0.80	STAT3 (0.73)	STAT3ALDH1A1KMT2AMEN1CDC25B
	SCHEMBL38650880	0.80	STAT3 (0.69)	STAT3ALDH1A1KMT2AMEN1CDC25B
	SCHEMBL6001021	0.80	ALDH1A1 (0.69)	STAT3ALDH1A1KMT2AMEN1CDC25B
	SCHEMBL16917433	0.78	STAT3 (0.76)	STAT3ALDH1A1KMT2AMEN1CDC25B
	SCHEMBL18691829	0.78	STAT3 (0.65)	STAT3ALDH1A1KMT2AMEN1CDC25B
	SCHEMBL18730820	0.77	STAT3 (0.69)	STAT3ALDH1A1KMT2AMEN1CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.