Eugenol

Eugenol

SCHEMBL1869592

C=CCc1ccc(O)c(OC)c1.CC=Cc1ccc(O)c(OC)c1C

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 8/20 0.65
ALOX5 P09917 5/20 0.65
ALDH1A1 P00352 2/20 0.65
PTGS1 P23219 2/20 0.65
CYP3A4 P08684 1/20 0.65
AR P10275 1/20 0.65
GABRA1 P14867 3/20 0.57
GABRB2 P47870 3/20 0.57
PPARG P37231 1/20 0.48
PPARD Q03181 1/20 0.48
PPARA Q07869 1/20 0.48
CNR2 P34972 1/20 0.45
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
TYR P14679 1/20 0.44
TRPA1 O75762 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eugenol SCHEMBL6664996 0.82 TRPM8 (0.70) TRPM8ALOX5ALDH1A1PTGS1CYP3A4
SCHEMBL27082230 0.82 ALOX5 (0.46) TRPM8ALOX5ALDH1A1PTGS1CYP3A4
Eugenol SCHEMBL2514503 0.81 ALDH1A1 (0.93) TRPM8ALOX5ALDH1A1PTGS1CYP3A4
Eugenol SCHEMBL788240 0.81 ALDH1A1 (1.00) TRPM8ALOX5ALDH1A1PTGS1CYP3A4
Eugenol SCHEMBL29364978 0.81 ALDH1A1 (1.00) TRPM8ALOX5ALDH1A1PTGS1CYP3A4
Eugenol SCHEMBL29126189 0.81 ALDH1A1 (1.00) TRPM8ALOX5ALDH1A1PTGS1CYP3A4
Eugenol SCHEMBL20361 0.81 ALDH1A1 (1.00) TRPM8ALOX5ALDH1A1PTGS1CYP3A4
Cis/Trans-Isoeugenol SCHEMBL18263901 0.80 TYR (0.70) ALOX5ALDH1A1PTGS1CYP3A4MAOA
Eugenol SCHEMBL1865810 0.80 ALOX5 (0.76) TRPM8ALOX5ALDH1A1PTGS1CYP3A4
Isoeugenol SCHEMBL1865809 0.80 ALOX5 (0.76) TRPM8ALOX5ALDH1A1PTGS1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2496682-A1 DELIVERY PARTICLE The Procter & Gamble Company (US) 2012-09-12 EP disclosed
WO-2011056935-A1 DELIVERY PARTICLE THE PROCTER & GAMBLE COMPANY (US) 2011-05-12 WO disclosed