SCHEMBL1869626

SCHEMBL1869626

N=C(N(c1ccccc1)c1ccccc1)N(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.55
ALDH1A1 P00352 4/20 0.50
KMT2A Q03164 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
MEN1 O00255 2/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
SIGMAR1 Q99720 1/20 0.46
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
ATM Q13315 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TRPM8 Q7Z2W7 1/20 0.40
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL28543340 0.97 NPSR1 (0.52) NPSR1ALDH1A1KMT2AL3MBTL1MEN1
SCHEMBL8133377 0.85 SIGMAR1 (0.49) NPSR1ALDH1A1KMT2AL3MBTL1MEN1
SCHEMBL8900621 0.78 NPSR1 (0.50) NPSR1ALDH1A1KMT2AL3MBTL1MEN1
SCHEMBL7529429 0.78 ALDH1A1 (0.58) NPSR1ALDH1A1KMT2AL3MBTL1MEN1
SCHEMBL940902 0.78 NPSR1 (0.50) NPSR1ALDH1A1KMT2AL3MBTL1MEN1
SCHEMBL36862 0.78 ALDH1A1 (0.58) NPSR1ALDH1A1KMT2AL3MBTL1MEN1
SCHEMBL1797820 0.78 ALDH1A1 (0.58) NPSR1ALDH1A1KMT2AL3MBTL1MEN1
SCHEMBL7527033 0.78 NPSR1 (0.40) NPSR1ALDH1A1KMT2AL3MBTL1MEN1
SCHEMBL7527037 0.78 NPSR1 (0.40) NPSR1ALDH1A1KMT2AL3MBTL1MEN1
SCHEMBL8334077 0.76 ALDH1A1 (0.45) NPSR1ALDH1A1KMT2AL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10023723-B2 Process for preparing rubber compositions and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-07-17 US claimed
CN-101765631-B Process for preparing rubber compositions and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2013-06-12 CN claimed
CN-101765631-A Process for preparing rubber compositions and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2010-06-30 CN claimed
EP-2152799-A1 PROCESS FOR PREPARING RUBBER COMPOSITIONS AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2010-02-17 EP claimed
WO-2008153876-A1 PROCESS FOR PREPARING RUBBER COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-12-18 WO claimed
US-20080306213-A1 Process for preparing rubber compositions and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS, INC. 2008-12-11 US claimed
EP-4569023-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2025-06-18 EP disclosed
WO-2024033348-A1 COMBINATION OF CATALYTIC COMPONENTS POLYU GMBH (DE) 2024-02-15 WO disclosed
EP-4321573-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2024-02-14 EP disclosed
EP-3018118-B1 BASE GENERATOR, BASE-REACTIVE COMPOSITION CONTAINING SAID BASE GENERATOR, AND BASE GENERATION METHOD FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2023-07-05 EP disclosed
CN-106574114-B Curable organopolysiloxane composition 瓦克化学股份公司 2019-10-15 CN disclosed
US-10428014-B2 Base generator, base-reactive composition containing said base generator, and base generation method FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-01 US disclosed
US-10301433-B2 Curable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2019-05-28 US disclosed
US-4704379-A Pressure sensitive manifold sheet KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1987-11-03 US disclosed
EP-0196484-A1 Pressure sensitive manifold sheet KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1986-10-08 EP disclosed
US-4602264-A Recording materials KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1986-07-22 US disclosed
EP-0017804-A1 Process for preparing polyurethane foams BAYER AG (DE) 1980-10-29 EP disclosed
US-4189542-A Process for the production of foam moldings having an impervious outer skin using semi-prepolymer prepared from isocyanates such as isophorone diisocyanate BAYER AKTIENGESELLSCHAFT (DE) 1980-02-19 US disclosed
EP-0001965-A1 Process for the preparation of foamed materials BAYER AG (DE) 1979-05-30 EP disclosed
US-4006124-A POLYURETHANES BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10428014-B2 Base generator, base-reactive composition containing said base generator, and base generation method HPRT1, GNG2, BLM NPSR1 2247/4885ALDH1A1 1468/4885KMT2A 1655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.