Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022681 | 0.85 | CALM1 (0.41) | NPSR1ALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL7078998 | 0.79 | NPSR1 (0.39) | NPSR1ALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL36862 | 0.79 | ALDH1A1 (0.58) | NPSR1ALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL7529429 | 0.79 | ALDH1A1 (0.58) | NPSR1ALDH1A1KMT2AL3MBTL1MEN1 | |
| Benzene SCHEMBL27899224 | 0.79 | ALDH1A1 (0.58) | NPSR1ALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL1797820 | 0.79 | ALDH1A1 (0.58) | NPSR1ALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL1869626 | 0.78 | NPSR1 (0.55) | NPSR1ALDH1A1KMT2AL3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL5813799 | 0.77 | ALDH1A1 (0.56) | NPSR1ALDH1A1KMT2AL3MBTL1MEN1 | |
| Hydrogen Sulfide SCHEMBL3400123 | 0.77 | ALDH1A1 (0.56) | NPSR1ALDH1A1KMT2AL3MBTL1MEN1 | |
| Bromide SCHEMBL668726 | 0.77 | ALDH1A1 (0.56) | NPSR1ALDH1A1KMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684127-A | SELECTIVELY PROTECTING AMINO GROUPS AND PHENOLIC HYDROXY GROUPS OF A PENTAPEPTIDE, OXIDIZING THE HYDROXYMETHYL MOIETY OF PROTECTED PENTAPEPTIDE TO CARBOXY, DEPROTECTING AMINO GROUP AND SUBMITTING COMPOUND TO DEGRADATION | GRUPPO LEPETIT SPA (IT) | 1997-11-04 | — | — | US | disclosed |
| US-5644025-A | AGLYCON DALBAHEPTIDE ANTIBIOTICS FOR CYCLIC TETRAPEPTIDES FOR BACTERICIDES | GRUPPO LEPETIT SPA (IT) | 1997-07-01 | — | — | US | disclosed |
| EP-0561827-B1 | TETRAPEPTIDES DERIVING FROM DALBAHEPTIDE ANTIBIOTICS | LEPETIT SPA (IT) | 1995-04-12 | — | — | EP | disclosed |
| EP-0561827-A1 | TETRAPEPTIDES DERIVING FROM DALBAHEPTIDE ANTIBIOTICS. | LEPETIT SPA (IT) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010517-A1 | TETRAPEPTIDES DERIVING FROM DALBAHEPTIDE ANTIBIOTICS | GRUPPO LEPETIT S.P.A. (IT) | 1992-06-25 | — | — | WO | disclosed |
| EP-0251760-A2 | Rubber composition | Bridgestone Corporation (JP) | 1988-01-07 | — | — | EP | disclosed |