Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12097911 | 0.83 | FYN (0.37) | — | |
| SCHEMBL19781618 | 0.74 | PDE5A (0.30) | PDE5A | |
| SCHEMBL16033029 | 0.72 | HTT (0.39) | ALDH1A1 | |
| SCHEMBL12097896 | 0.71 | CYP2A6 (0.41) | — | |
| SCHEMBL1870362 | 0.66 | PIK3CB (0.32) | ALDH1A1 | |
| SCHEMBL11880227 | 0.66 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1865755 | 0.66 | MAP3K14 (0.43) | ALDH1A1 | |
| SCHEMBL30063374 | 0.66 | TRIM24 (0.37) | ALDH1A1 | |
| SCHEMBL7986168 | 0.66 | DYRK1B (0.41) | ALDH1A1 | |
| SCHEMBL29951190 | 0.66 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741932-B2 | Imidazopyridine derivatives | Piramal Enterprises Limited (IN) | 2014-06-03 | — | — | US | disclosed |
| US-20120232072-A1 | IMIDAZOPYRIDINE DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2012-09-13 | — | — | US | disclosed |
| WO-2011055320-A1 | IMIDAZOPYRIDINE DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232072-A1 | IMIDAZOPYRIDINE DERIVATIVES | IL6, IL6ST, STAT3 | ALDH1A1 2629/4885PDE5A 1860/4885KDM4C 2270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.