Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1163131 | 0.79 | DYRK1A (0.54) | ALDH1A1DYRK1ADYRK2DYRK1BDYRK3 | |
| SCHEMBL31003154 | 0.72 | MALT1 (0.39) | ALDH1A1DYRK1ADYRK2DYRK1BDYRK3 | |
| SCHEMBL24998130 | 0.71 | MAPK1 (0.44) | ALDH1A1FYN | |
| SCHEMBL14639038 | 0.69 | MKNK1 (0.49) | ALDH1A1DYRK1ADYRK2DYRK1BDYRK3 | |
| SCHEMBL1865755 | 0.68 | MAP3K14 (0.43) | ALDH1A1DYRK1ADYRK2DYRK1BDYRK3 | |
| SCHEMBL1869658 | 0.66 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL15674084 | 0.66 | TGFBR1 (0.34) | DYRK1ADYRK2DYRK1BDYRK3CCNT1 | |
| SCHEMBL452453 | 0.66 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL23726938 | 0.66 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL3302899 | 0.64 | AHR (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |