SCHEMBL186969

SCHEMBL186969

Cc1cc(N)ccc1-c1ccc(N)c(C)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
CASP1 P29466 4/20 0.46
PDE10A Q9Y233 1/20 0.43
POLB P06746 2/20 0.41
MAPT P10636 4/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
THRB P10828 3/20 0.39
GAA P10253 2/20 0.39
NR4A1 P22736 1/20 0.39
PTK2B Q14289 1/20 0.39
TSHR P16473 5/20 0.39
CYP3A4 P08684 4/20 0.39
KDM4E B2RXH2 3/20 0.38
LMNA P02545 2/20 0.38
ALOX15 P16050 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
PIK3CA P42336 1/20 0.36
PLA2G7 Q13093 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29103604 0.89 ALDH1A1 (0.43) ALDH1A1CASP1PDE10APOLBMAPT
SCHEMBL29006686 0.89 ALDH1A1 (0.42) ALDH1A1CASP1PDE10APOLBMAPT
SCHEMBL30839745 0.84 ALDH1A1 (0.65) ALDH1A1CASP1PDE10APOLBMAPT
SCHEMBL63910 0.84 ALDH1A1 (0.65) ALDH1A1CASP1PDE10APOLBMAPT
SCHEMBL16280579 0.84 ALDH1A1 (0.65) ALDH1A1CASP1PDE10APOLBMAPT
SCHEMBL29777463 0.84 ALDH1A1 (0.65) ALDH1A1CASP1PDE10APOLBMAPT
SCHEMBL30839804 0.84 CYP3A4 (0.48) ALDH1A1CASP1PDE10APOLBMAPT
SCHEMBL29683594 0.84 CYP3A4 (0.48) ALDH1A1CASP1PDE10APOLBMAPT
SCHEMBL3784789 0.84 CYP3A4 (0.48) ALDH1A1CASP1PDE10APOLBMAPT
SCHEMBL5437682 0.82 ALDH1A1 (0.62) ALDH1A1CASP1PDE10APOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140113316-A1 DEVICE, METHOD AND KIT FOR THE DETECTION OF DIFFERENT MARKERS IN DIFFERENT CELLULAR OR MOLECULAR TYPES AND THEIR QUANTIFICATIONS MAZZEO ALESSANDRA (IT) 2014-04-24 US claimed
JP-63091563-A None JP disclosed
US-20260035433-A1 PD-L1 ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE AKSTON BIOSCIENCES CORP (US) 2026-02-05 US disclosed
US-20260035414-A1 HERV-K (HML-2) ENV ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE UNITED STATES GOVERNMENT 2026-02-05 US disclosed
US-20260035415-A1 HERV-K (HML-2) ENV ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE UNITED STATES GOVERNMENT 2026-02-05 US disclosed
EP-4676530-A2 NUCLEOCAPSID ANTIGEN IMMUNOTHERAPY FOR COVID-19 FUSION PROTEINS AND METHODS OF USE Vakston, Inc. (US) 2026-01-14 EP disclosed
US-12454565-B2 PD-L1 analog fusion proteins for antigen specific immunotherapy and methods of use AKSTON BIOSCIENCES CORPORATION (US) 2025-10-28 US disclosed
US-20250296978-A1 PD-L1 ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE AKSTON BIOSCIENCES CORPORATION 2025-09-25 US disclosed
WO-2024186803-A2 NUCLEOCAPSID ANTIGEN IMMUNOTHERAPY FOR COVID-19 FUSION PROTEINS AND METHODS OF USE AKSTON BIOSCIENCES CORPORATION (US) 2024-09-12 WO disclosed
US-20230149448-A1 METHODS FOR PREVENTING AND TREATING RESPIRATORY INFECTIONS VIA MODIFICATION OF VIRUS RECEPTOR BINDING DOMAINS USING HYPOHALOUS ACIDS BT MANUFACTURING, LLC 2023-05-18 US disclosed
US-5932430-A DETECTING HELIOBACTER PYLORI ANTIGENS SAMPLE USING SENSITIVE AND ACCURATE SANDWICH ASSAY MERIDIAN DIAGNOSTICS, INC. (US) 1999-08-03 US disclosed
US-5871942-A HELICOBACTER FOR GASTROINTESTINAL DISORDERS AND POLYCLONAL ANTIBODIES MERIDIAN DIAGNOSTICS, INC. (US) 1999-02-16 US disclosed
WO-1998039647-A1 ASYMMETRICAL FLOW-FIELD FLOW FRACTIONATING DEVICE KLEIN THORSTEN (DE) 1998-09-11 WO disclosed
WO-1998027115-A1 OIL BODIES AND ASSOCIATED PROTEINS AS AFFINITY MATRICES SEMBIOSYS GENETICS INC. (CA) 1998-06-25 WO disclosed
US-5716791-A DILUTION; USING A POLYCLONAL ANTIBODY MERIDIAN DIAGNOSTICS, INC. (US) 1998-02-10 US disclosed
CN-1165299-A Immunoassay for helicobacter pylori in fecal specimens MERIDIAN DIAGNOSTICS INC (US) 1997-11-19 CN disclosed
EP-0806667-A1 Immunoassay for h. pylori in fecal specimens MERIDIAN DIAGNOSTICS, INC. (US) 1997-11-12 EP disclosed
EP-0180564-B1 IMMUNOGENIC COMPLEX, A METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AN IMMUNE STIMULANT, VACCINES AND REAGENTS Morein, Bror (SE) 1991-07-17 EP disclosed
EP-0407172-A1 Aromatic polyimide separation membrane MITSUBISHI KASEI CORPORATION (JP) 1991-01-09 EP disclosed
JP-S6391563-A EXAMINATION OF PROTEIN SPECIFIC ANTIGEN DERIVED FROM BACTERIA NITSUSUI SEIYAKU KK 1988-04-22 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035415-A1 HERV-K (HML-2) ENV ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE HM13, MYOF, SMN1; SMN2 ALDH1A1 4843/4885CASP1 1523/4885PDE10A 4850/4885
US-20260035433-A1 PD-L1 ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE PDCD1LG2, CD274, PDCD1 ALDH1A1 3953/4885CASP1 1861/4885PDE10A 4047/4885
US-20260035414-A1 HERV-K (HML-2) ENV ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE SMN1; SMN2, FUS, MORF4L1 ALDH1A1 4845/4885CASP1 1254/4885PDE10A 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.