Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697222 | 0.84 | KLKB1 (0.38) | KLKB1 | |
| SCHEMBL19354570 | 0.79 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL25400513 | 0.77 | EGLN1 (0.43) | HPGDSEGLN1SLC22A12 | |
| SCHEMBL31264140 | 0.77 | EGLN1 (0.43) | HPGDSEGLN1SLC22A12 | |
| SCHEMBL18459010 | 0.77 | MET (0.48) | KLKB1 | |
| SCHEMBL23279828 | 0.74 | HPGDS (0.41) | HPGDSKLKB1ACACBCCNCCDK8 | |
| SCHEMBL20282952 | 0.73 | KLKB1 (0.36) | KLKB1 | |
| SCHEMBL20282810 | 0.72 | KLKB1 (0.39) | KLKB1 | |
| SCHEMBL17442585 | 0.69 | HPGDS (0.44) | HPGDSKLKB1ACACBCCNCCDK8 | |
| SCHEMBL17442542 | 0.67 | HPGDS (0.44) | HPGDSKLKB1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611252-B2 | Therapeutic inhibitory compounds | LIFESCI PHARMACEUTICALS, INC. (BB) | 2017-04-04 | — | — | US | disclosed |