Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20282810 | 0.89 | KLKB1 (0.39) | KLKB1MAP4K1 | |
| SCHEMBL20282946 | 0.77 | KLKB1 (0.36) | KLKB1MAP4K1 | |
| SCHEMBL21657099 | 0.75 | KLKB1 (0.46) | KLKB1MAP4K1 | |
| SCHEMBL18697214 | 0.74 | KLKB1 (0.33) | KLKB1 | |
| SCHEMBL18697152 | 0.73 | HPGDS (0.33) | KLKB1 | |
| SCHEMBL18458818 | 0.72 | KLKB1 (0.47) | KLKB1MAP4K1 | |
| SCHEMBL18697219 | 0.72 | PTGDR2 (0.30) | — | |
| SCHEMBL17442576 | 0.71 | KLKB1 (0.41) | KLKB1MAP4K1PARP1 | |
| SCHEMBL23279792 | 0.69 | KLKB1 (0.35) | KLKB1MAP4K1 | |
| SCHEMBL18697211 | 0.69 | KLKB1 (0.39) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266515-B2 | Therapeutic inhibitory compounds | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-04-23 | — | — | US | disclosed |
| US-20180170906-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS, INC. | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170906-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | KLKB1, SERPINB1, SERPINE1 | KLKB1 1/4885MAP4K1 249/4885PARP1 1139/4885 |
| US-10266515-B2 | Therapeutic inhibitory compounds | KLKB1, SERPINB1, SERPINE1 | KLKB1 1/4885MAP4K1 249/4885PARP1 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.