Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20282810 | 0.86 | KLKB1 (0.39) | KLKB1 | |
| SCHEMBL18697222 | 0.82 | KLKB1 (0.38) | KLKB1 | |
| SCHEMBL19780593 | 0.78 | KLKB1 (0.37) | KLKB1 | |
| SCHEMBL20282952 | 0.74 | KLKB1 (0.36) | KLKB1 | |
| SCHEMBL21177281 | 0.74 | SIRT1 (0.38) | KLKB1 | |
| SCHEMBL21179410 | 0.73 | HSP90AB1 (0.42) | KLKB1 | |
| SCHEMBL21179367 | 0.73 | KLKB1 (0.36) | KLKB1 | |
| SCHEMBL20616461 | 0.72 | KLKB1 (0.31) | KLKB1 | |
| SCHEMBL21179353 | 0.71 | KLKB1 (0.36) | KLKB1 | |
| SCHEMBL19779861 | 0.71 | CYP1A2 (0.38) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611252-B2 | Therapeutic inhibitory compounds | LIFESCI PHARMACEUTICALS, INC. (BB) | 2017-04-04 | — | — | US | disclosed |