Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 7/20 | 0.39 |
| ▸ | MMP9 | P14780 | 6/20 | 0.39 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697263 | 0.78 | POLB (0.40) | ALDH1A1 | |
| SCHEMBL2676051 | 0.77 | CRBN (0.33) | CRBNDDB1HTR2AKCNH2 | |
| SCHEMBL18697200 | 0.75 | MMP2 (0.32) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL10151268 | 0.73 | SSTR5 (0.33) | CRBNKCNH2 | |
| SCHEMBL18697247 | 0.71 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL18697223 | 0.71 | L3MBTL1 (0.31) | ALDH1A1 | |
| SCHEMBL18697246 | 0.71 | L3MBTL1 (0.31) | — | |
| SCHEMBL11140841 | 0.71 | CRBN (0.34) | CRBNDDB1 | |
| SCHEMBL18697243 | 0.70 | SIGMAR1 (0.34) | — | |
| SCHEMBL2976287 | 0.70 | CRBN (0.36) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440557-B1 | NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS | BASF SE (DE) | 2017-04-05 | — | — | EP | disclosed |