Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19233211 | 0.87 | TRPV1 (0.46) | TRPV1POLBHTTNAMPT | |
| SCHEMBL14314081 | 0.81 | TRPV1 (0.39) | TRPV1POLB | |
| SCHEMBL20031971 | 0.74 | HDAC3 (0.45) | POLB | |
| SCHEMBL24600209 | 0.74 | PLK1 (0.46) | POLBPLK1 | |
| SCHEMBL13901420 | 0.74 | POLB (0.54) | POLB | |
| SCHEMBL20932834 | 0.73 | POLB (0.39) | POLB | |
| SCHEMBL25893618 | 0.73 | TRPV1 (0.45) | TRPV1 | |
| SCHEMBL16592004 | 0.72 | ALDH1A1 (0.42) | HTT | |
| SCHEMBL1961940 | 0.71 | TRPV1 (0.58) | TRPV1HTT | |
| SCHEMBL22508202 | 0.70 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9610355-B2 | Carrier nanoparticles and related compositions, methods and systems | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-04-04 | — | — | US | disclosed |