Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697940 | 0.87 | TRPV1 (0.42) | TRPV1POLBHTTNAMPT | |
| SCHEMBL14314081 | 0.83 | TRPV1 (0.39) | TRPV1POLBNPC1RAB9A | |
| SCHEMBL18652074 | 0.81 | TRPV1 (0.44) | TRPV1HTTNAMPTRAB9A | |
| SCHEMBL18646429 | 0.81 | POLB (0.40) | TRPV1POLBEGLN1HTTNAMPT | |
| SCHEMBL19465881 | 0.78 | POLB (0.38) | POLB | |
| SCHEMBL1961940 | 0.75 | TRPV1 (0.58) | TRPV1HTT | |
| SCHEMBL23870191 | 0.75 | AOC3 (0.40) | POLBHTTNPC1RAB9A | |
| SCHEMBL17635466 | 0.73 | TRPV1 (0.44) | TRPV1POLBNPC1RAB9A | |
| SCHEMBL18698021 | 0.72 | TRPV1 (0.46) | TRPV1HTTNAMPTRAB9A | |
| SCHEMBL20932834 | 0.72 | POLB (0.39) | POLBNPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134188-A1 | NOVEL DIHYDROPYRIDINONE AND DIHYDROPYRIMIDINONE COMPOUNDS AND THEIR USE | UNIVERSITE DE LILLE 2 DROIT ET SANTE (FR) | 2017-08-10 | — | — | WO | disclosed |