Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.36 |
| ▸ | RXRA | P19793 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17808271 | 0.86 | MAPT (0.40) | MAPTJUNNFKB1NFKB2RELA | |
| SCHEMBL16454401 | 0.80 | JUN (0.43) | MAPTJUNNFKB1NFKB2RELA | |
| SCHEMBL17796812 | 0.78 | MAPT (0.45) | MAPTJUNNFKB1NFKB2RELA | |
| SCHEMBL8559321 | 0.75 | MAPT (0.43) | MAPTJUNNFKB1NFKB2RELA | |
| SCHEMBL28950798 | 0.73 | NFKB1 (0.40) | MAPTJUNNFKB1NFKB2RELA | |
| SCHEMBL18699192 | 0.72 | GABRA1 (0.36) | GAANPSR1KDM4EARALDH1A1 | |
| SCHEMBL17816209 | 0.70 | MAPT (0.39) | MAPTGAANPSR1KDM4EMEN1 | |
| SCHEMBL16455673 | 0.69 | POLB (0.47) | MAPTJUNNFKB1NFKB2RELA | |
| SCHEMBL13468557 | 0.69 | KDM4E (0.56) | MAPTJUNNFKB1NFKB2RELA | |
| SCHEMBL16446943 | 0.68 | JUN (0.35) | MAPTJUNNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611248-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2017-04-04 | — | — | US | disclosed |