SCHEMBL62433

SCHEMBL62433

O=C1OC(=O)C2CCCC1C2

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
GMNN O75496 1/20 0.39
PPM1B O75688 1/20 0.39
LMNA P02545 1/20 0.39
PPP1CC P36873 1/20 0.39
TFPI2 P48307 1/20 0.39
RAB9A P51151 1/20 0.39
PPP5C P53041 1/20 0.39
PPP1CA P62136 1/20 0.39
PMP22 Q01453 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TP53 P04637 1/20 0.39
CYP2D6 P10635 1/20 0.39
NFKB1 P19838 1/20 0.39
THPO P40225 1/20 0.39
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3764057 1.00 KDM4E (0.39) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL23895076 1.00 KDM4E (0.39) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL20646727 0.97 KDM4E (0.37) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL10680562 0.94 KDM4E (0.39) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL23380386 0.91 KDM4E (0.33) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL19485747 0.91 ALDH1A1 (0.36) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL18700017 0.88 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL20428057 0.88 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL3721811 0.88 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL2709834 0.88 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1149836-B1 Polynalbuphine derivatives HU OLIVER YOA PU (TW) 2003-02-26 EP claimed
EP-1149836-A1 Polynalbuphine derivatives Hu, Oliver Yoa-Pu (TW) 2001-10-31 EP claimed
US-5017679-A Polyesters terminated with carboxycyclohexanecarboxylate groups EASTMAN KODAK COMPANY (US) 1991-05-21 US claimed
US-12637405-B2 Integrated process for generating acid anhydrides CLEANTECH BUILDING MATERIALS PLC (GB) 2026-05-26 US disclosed
US-20250304521-A1 PROCESS FOR GENERATING ACID ANHYDRIDES CLEANTECH BUILDING MATERIALS PLC (GB) 2025-10-02 US disclosed
US-12358860-B2 Process for generating acid anhydrides CLEANTECH BUILDING MATERIALS PLC (GB) 2025-07-15 US disclosed
CN-118852152-A Pyridazinone compound and preparation method and application thereof 国科大杭州高等研究院 2024-10-29 CN disclosed
WO-2024097923-A1 INTEGRATED PROCESS FOR GENERATING ACID ANHYDRIDES HYCONIX, INC. (US) 2024-05-10 WO disclosed
CN-117987189-A Modified castor oil diesel antiwear agent, preparation method thereof and diesel composition 中国石油化工股份有限公司 2024-05-07 CN disclosed
EP-4334280-A1 INTEGRATED PROCESS FOR GENERATING ACID ANHYDRIDES Hyconix, Inc. (US) 2024-03-13 EP disclosed
CN-117677602-A Integrated process for producing anhydrides 纮康公司 2024-03-08 CN disclosed
US-5017679-A Polyesters terminated with carboxycyclohexanecarboxylate groups EASTMAN KODAK COMPANY (US) 1991-05-21 US disclosed
US-4985490-A EMULSION REACTION, SURFACTANT TO PREVENT AGGLOMERATION, PIGMENT INCORPORATED DURING POLYMERIZATION BAYER AKTIENGESELLSCHAFT (DE) 1991-01-15 US disclosed
EP-0394789-A1 Continuous process for the production of powdered polyisocyanate addition products and the powders produced therefrom BAYER AG (DE) 1990-10-31 EP disclosed
EP-0392285-A2 Method of direct manufacture of pigmented polyurethane powder BAYER AG (DE) 1990-10-17 EP disclosed
US-4940750-A Continuous process for the production of powdered polyisocyanate addition products and the powders produced therefrom BAYER AKTIENGESELLSCHAFT (DE) 1990-07-10 US disclosed
EP-0309544-A1 PSYCHOTROPIC BICYCLIC IMIDES. AMERICAN HOME PROD (US) 1989-04-05 EP disclosed
WO-1988007530-A1 PSYCHOTROPIC BICYCLIC IMIDES AMERICAN HOME PRODUCTS CORPORATION (US) 1988-10-06 WO disclosed
US-4748240-A Psychotropic bicyclic imides AMERICAN HOME PRODUCTS CORPORATION (US) 1988-05-31 US disclosed
EP-0268369-A1 Bridged bicyclic imides as anxiolytics and antidepressants PFIZER INC. (US) 1988-05-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304521-A1 PROCESS FOR GENERATING ACID ANHYDRIDES CA1, CA9, CA6 KDM4E 3120/4885GMNN 793/4885PPM1B 1392/4885
US-12358860-B2 Process for generating acid anhydrides CA1, CA9, CA6 KDM4E 3120/4885GMNN 793/4885PPM1B 1392/4885
US-12637405-B2 Integrated process for generating acid anhydrides GRHPR, GCDH, OGDH KDM4E 2588/4885GMNN 1254/4885PPM1B 3209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.