Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | F2R | P25116 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17305367 | 0.80 | F2R (0.39) | S1PR1S1PR5TP53ALDH1A1F2R | |
| SCHEMBL18700254 | 0.75 | SLC6A2 (0.40) | ALDH1A1HTTHRH3RAB9ASLC6A3 | |
| SCHEMBL18702403 | 0.72 | OPRK1 (0.37) | TP53ALDH1A1F2RNPC1MAPT | |
| SCHEMBL26483314 | 0.67 | ESRRG (0.41) | POLBS1PR1S1PR5F2RNPC1 | |
| SCHEMBL25004757 | 0.66 | MAPT (0.40) | ALDH1A1HRH3MAPTSMN1; SMN2CYP2D6 | |
| SCHEMBL22275971 | 0.65 | CHRM2 (0.49) | ALDH1A1HTTCHRM2CYP2D6CHRM3 | |
| SCHEMBL23514656 | 0.65 | OPRD1 (0.38) | POLBHRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17305234 | 0.64 | RORC (0.43) | — | |
| SCHEMBL17305262 | 0.64 | MAPK1 (0.38) | MAPTCYP2D6 | |
| SCHEMBL17305219 | 0.64 | CYP2C9 (0.35) | ALDH1A1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150578-A1 | NOVEL PYRROLIDINE COMPOUND AND APPLICATION AS MELANOCORTIN RECEPTOR AGONIST | Mitsubishi Tanabe Pharma Corporation (JP) | 2017-04-05 | — | — | EP | disclosed |