SCHEMBL187025

SCHEMBL187025

O=C(OC(=O)C(Cl)Cl)C(Cl)Cl

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1083281 0.86 LMNA (0.39) LMNA
SCHEMBL8523741 0.86 LMNA (0.39) LMNA
SCHEMBL8586196 0.85 ALDH1A1 (0.36) LMNAALDH1A1
SCHEMBL9781203 0.81
SCHEMBL187026 0.81
SCHEMBL4645074 0.81
SCHEMBL20302569 0.78 ALDH1A1 (0.38) LMNAALDH1A1
SCHEMBL7509907 0.77 LMNA (0.44) LMNAALDH1A1
SCHEMBL11331394 0.76
SCHEMBL7153541 0.76 LMNA (0.32) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4013738-B1 PROCESS FOR PREPARING 1-INDANONE COMPOUNDS BY INTRAMOLECULAR FRIEDEL-CRAFTS REACTION OF ALPHA,ALPHA-DIALKYLMALONATE DERIVATIVES FIRMENICH & CIE (CH) 2026-02-25 EP claimed
CN-119948043-A Method for producing oligonucleotide 住友化学株式会社 2025-05-06 CN claimed
US-20250051256-A1 PRODUCTION METHOD FOR PURIFIED DICHLOROACETIC ACID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-02-13 US claimed
EP-4477659-A1 METHOD FOR PRODUCING OLIGONUCLEOTIDE Sumitomo Chemical Company, Limited (JP) 2024-12-18 EP claimed
EP-4410770-A1 PRODUCTION METHOD FOR PURIFIED DICHLOROACETIC ACID Sumitomo Chemical Company, Limited (JP) 2024-08-07 EP claimed
CN-118271407-A Multi-specific platinum (IV) anticancer agent for simultaneously interfering tumor energy metabolism and vascular production, and preparation method and application thereof 南京师范大学 2024-07-02 CN claimed
CN-117980285-A Process for producing purified dichloroacetic acid 住友化学株式会社 2024-05-03 CN claimed
WO-2024089953-A1 METHOD FOR PRODUCING OLIGONUCLEOTIDE 住友化学株式会社 2024-05-02 WO claimed
US-11952335-B2 Process for preparing 1-indanone compounds by intramolecular Friedel-Crafts reaction of alpha,alpha-dialkylmalonate derivatives FIRMENICH SA (CH) 2024-04-09 US claimed
WO-2023186187-A1 LIQUID CRYSTAL POLYMER, AND PREPARATION METHOD AND USE THEREFOR 珠海万通特种工程塑料有限公司 2023-10-05 WO claimed
EP-0560059-A2 Abrasive articles including a crosslinked siloxane MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-09-15 EP claimed
WO-1993016142-A1 MOISTURE CURABLE POLYSILOXANE RELEASE COATING COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-19 WO claimed
US-5221739-A Acetylation of 3-hydroxymethyl cephalosporins ELI LILLY AND COMPANY (US) 1993-06-22 US claimed
US-5213589-A Reduced loading, reduced transfer of pressure sensitive adhesive when stacked or rolled MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-25 US claimed
EP-0247620-B1 PRODUCTION OF CYCLOPENTENONES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-05 EP claimed
US-4957867-A Production of cyclopentenones by enzyme resolution SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-09-18 US claimed
EP-0247620-A2 Production of cyclopentenones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-12-02 EP claimed
EP-0239194-A2 Methods for preparing hydroxy compounds and intermediates SYMBICOM AB (SE) 1987-09-30 EP claimed
EP-0168293-B1 PROCESS FOR PREPARING TRIFLUOROACETIC ANHYDRIDE RHONE-POULENC CHIMIE (FR) 1987-08-05 EP claimed
US-4595541-A Process for the preparation of trifluoroacetic anhydride RHONE POULENC SPECIALTIES CHIMIQUES (FR) 1986-06-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11952335-B2 Process for preparing 1-indanone compounds by intramolecular Friedel-Crafts reaction of alpha,alpha-dialkylmalonate derivatives IP6K1, FDFT1, MINK1 LMNA 1042/4885ALDH1A1 149/4885
US-20250051256-A1 PRODUCTION METHOD FOR PURIFIED DICHLOROACETIC ACID DERA, DDC, POLI LMNA 1355/4885ALDH1A1 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.