Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 10/20 | 0.44 |
| ▸ | MASP2 | O00187 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 3/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870902 | 0.93 | MASP2 (0.43) | KLKB1MASP2KLK1METTL3METTL14 | |
| SCHEMBL1867150 | 0.93 | MASP2 (0.43) | KLKB1MASP2KLK1METTL3METTL14 | |
| SCHEMBL1867894 | 0.93 | MASP2 (0.43) | KLKB1MASP2KLK1METTL3METTL14 | |
| SCHEMBL1861128 | 0.91 | MASP2 (0.44) | KLKB1MASP2KLK1 | |
| SCHEMBL1871181 | 0.91 | MASP2 (0.43) | KLKB1MASP2KLK1CHRNA7 | |
| SCHEMBL1874196 | 0.91 | MASP2 (0.43) | KLKB1MASP2KLK1CHRNA7 | |
| SCHEMBL1870064 | 0.90 | MASP2 (0.42) | KLKB1MASP2KLK1 | |
| SCHEMBL1867433 | 0.88 | MASP2 (0.42) | KLKB1MASP2KLK1CHRNA7 | |
| SCHEMBL1870717 | 0.88 | MASP2 (0.46) | KLKB1MASP2KLK1 | |
| Trifluoroacetic Acid SCHEMBL1873249 | 0.88 | DPP4 (0.43) | KLKB1MASP2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |