Sugi Predict

Sugi Predict / Compounds / SCHEMBL18705376

SCHEMBL18705376

SCHEMBL18705376

O=C1OC(O)c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.53
▸ HSD17B10 Q99714 2/20 0.42
▸ GAA P10253 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ LMNA P02545 2/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ RECQL P46063 1/20 0.40
▸ POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15314185 1.00 ALDH1A1 (0.53) ALDH1A1HSD17B10GAAKDM4ELMNA
SCHEMBL228037 1.00 ALDH1A1 (0.53) ALDH1A1HSD17B10GAAKDM4ELMNA
SCHEMBL31315628 1.00 ALDH1A1 (0.53) ALDH1A1HSD17B10GAAKDM4ELMNA
SCHEMBL29791776 0.78 ALDH1A1 (0.59) ALDH1A1HSD17B10GAAKDM4EMEN1
SCHEMBL17769033 0.78 TYMS (0.48) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL21881721 0.77 APEX1 (0.38) ALDH1A1GAAKDM4ELMNAMEN1
SCHEMBL11109865 0.76 MAOB (0.45) ALDH1A1HSD17B10KDM4E
SCHEMBL18705354 0.76 MAOA (0.35) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL23771080 0.75 POLB (0.39) ALDH1A1HSD17B10GAAKDM4EMEN1
SCHEMBL31084351 0.75 POLB (0.39) ALDH1A1HSD17B10GAAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118373791-A Allyl phthalide compound and preparation method and application thereof 南京工业大学 2024-07-23 — — CN claimed
CN-108794405-B Method for continuously preparing Olaparib intermediate by adopting micro-channel modular reaction device 南京工业大学 2020-09-04 — — CN claimed
WO-2025089351-A1 RESIST COMPOSITION, RESIST PATTERN FORMING METHOD, COMPOUND, AND POLYMER COMPOUND 東京応化工業株式会社 2025-05-01 — — WO disclosed
CN-119192108-A Preparation method of chiral phthaloyl ester prodrug 贵州大学 2024-12-27 — — CN disclosed
WO-2024210024-A1 RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, COMPOUND, AND POLYMER COMPOUND 東京応化工業株式会社 2024-10-10 — — WO disclosed
US-20240327375-A1 SUBSTITUTED HETEROBICYCLIC DERIVATIVES AS NEGATIVE ALLOSTERIC MODULATORS OF MGLU7 RECEPTOR ADDEX PHARMA S.A. (CH) 2024-10-03 — — US disclosed
CN-118373791-A Allyl phthalide compound and preparation method and application thereof 南京工业大学 2024-07-23 — — CN disclosed
US-12037443-B2 Polymeric materials with improved environmental durability Westlake Royal Building Products Inc. (US) 2024-07-16 — — US disclosed
US-12037304-B2 Monomer and polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-07-16 — — US disclosed
EP-4337643-A1 SUBSTITUTED HETEROBICYCLIC DERIVATIVES AS NEGATIVE ALLOSTERIC MODULATORS OF MGLU7 RECEPTOR Addex Pharma S.A (CH) 2024-03-20 — — EP disclosed
US-11919857-B2 Phthalide derivative, preparation method and use thereof LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2024-03-05 — — US disclosed
US-7196085-B2 Phthalazinone derivatives KUDOS PHARMACEUTICALS LIMITED (GB) 2007-03-27 — — US disclosed
US-7196085-B2 Phthalazinone derivatives KUDOS PHARMACEUTICALS LIMITED (GB) 2007-03-27 — — US disclosed
US-20070031514-A1 Use of isoindolinone derivatives as insecticides BAYER CROPSCIENCE AG (DE) 2007-02-08 — — US disclosed
US-20070031514-A1 Use of isoindolinone derivatives as insecticides BAYER CROPSCIENCE AG (DE) 2007-02-08 — — US disclosed
US-20070027147-A1 Biarylurea derivatives MSD K.K. (JP) 2007-02-01 — — US disclosed
WO-2006021801-A1 4-HETEROARYLMETHYL SUBSTITUTED PHTHALAZINONE DERIVATIVES KUDOS PHARMACEUTICALS LIMITED (GB) 2006-03-02 — — WO disclosed
CN-1675212-A 8- [ 3-amino-piperidin-1-yl ] -xanthines, process for their preparation and their use as pharmaceutical preparations BOEHRINGER INGELHEIM PHARMA (DE) 2005-09-28 — — CN disclosed
WO-2004080976-A1 PHTHALAZINONE DERIVATIVES KUDOS PHARMACEUTICALS LIMITED (GB) 2004-09-23 — — WO disclosed
CN-1492870-A Xanthine derivatives, process for their preparation and their use as pharmaceutical compositions ���ָ��Ӣ��ķ�������Ϲ�˾ 2004-04-28 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070031514-A1 Use of isoindolinone derivatives as insecticides DDT, CYP1A2, CYP1A1 ALDH1A1 47/4885HSD17B10 821/4885GAA 4457/4885
US-20070027147-A1 Biarylurea derivatives CDK6, CDK4, CCNI ALDH1A1 935/4885HSD17B10 1895/4885GAA 3502/4885
US-11919857-B2 Phthalide derivative, preparation method and use thereof HDAC6, NQO1, UGT2B7 ALDH1A1 125/4885HSD17B10 220/4885GAA 566/4885
US-20240327375-A1 SUBSTITUTED HETEROBICYCLIC DERIVATIVES AS NEGATIVE ALLOSTERIC MODULATORS OF MGLU7 RECEPTOR GRM7, GRM2, GRM1 ALDH1A1 3508/4885HSD17B10 3270/4885GAA 4270/4885
US-12037304-B2 Monomer and polymer, compensation film, optical film, and display device PYM1, RAD51, CRY1 ALDH1A1 326/4885HSD17B10 4593/4885GAA 3927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.