Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 10/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551637 | 0.86 | — | — | |
| SCHEMBL18236910 | 0.85 | GPR88 (0.36) | DRD4NAMPTPDCD1CD274 | |
| SCHEMBL5360130 | 0.83 | KCNH3 (0.37) | NAMPTMAP4K4 | |
| SCHEMBL5324869 | 0.83 | SAT1 (0.38) | DRD4NAMPTPDCD1CD274MAP4K4 | |
| SCHEMBL1249532 | 0.83 | DRD4 (0.36) | DRD4NAMPTPDCD1CD274MAP4K4 | |
| SCHEMBL14838846 | 0.80 | — | — | |
| SCHEMBL14143341 | 0.80 | — | — | |
| SCHEMBL321562 | 0.80 | — | — | |
| SCHEMBL6353032 | 0.80 | — | — | |
| SCHEMBL17288790 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080033154-A1 | Process for Producing 3-Aminomethyltetrahydrofuran Derivative | MITSUI CHEMICALS, INC. (JP) | 2008-02-07 | — | — | US | disclosed |
| US-20080033154-A1 | Process for Producing 3-Aminomethyltetrahydrofuran Derivative | MITSUI CHEMICALS, INC. (JP) | 2008-02-07 | — | — | US | disclosed |
| EP-1123270-B1 | PREPARATION OF AMINES | EASTMAN CHEM CO (US) | 2003-12-10 | — | — | EP | disclosed |
| EP-1123270-A1 | PREPARATION OF AMINES | EASTMAN CHEMICAL COMPANY (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024703-A1 | PREPARATION OF AMINES | EASTMAN CHEMICAL COMPANY (US) | 2000-05-04 | — | — | WO | disclosed |
| US-5990323-A | CONTACTING IN A REACTION ZONE A WATER-SOLUBLE ALDEHYDE, WATER, AMMONIA AND HYDROGEN IN THE PRESENCE OF A SUPPORTED RUTHENIUM CATALYST AT A TEMPERATURE OF ABOUT 60 TO 150 DEGREE C. AND A TOTAL PRESSURE OF ABOUT 7 TO 50 BAR ABSOLUTE. | EASTMAN CHEMICAL COMPANY (US) | 1999-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033154-A1 | Process for Producing 3-Aminomethyltetrahydrofuran Derivative | ALAD, ACMSD, HPD | DRD4 2353/4885NAMPT 585/4885PDCD1 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.