SCHEMBL5360130

SCHEMBL5360130

C1CC(CNCC2CCOCC2)CCO1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 1/20 0.37
SAT1 P21673 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
GBA1 P04062 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH4 P08319 1/20 0.32
ADH7 P40394 1/20 0.32
NAMPT P43490 2/20 0.32
KDM1A O60341 2/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
EPHX2 P34913 1/20 0.31
MAP4K4 O95819 1/20 0.30
VNN1 O95497 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28707592 0.85 NPC1 (0.34) KCNH3SAT1NPC1RAB9AGBA1
SCHEMBL4572204 0.85 SAT1 (0.48) KCNH3SAT1NPC1RAB9AGBA1
SCHEMBL1870892 0.84 HPGD (0.34) KCNH3ALDH1A1KDM1A
SCHEMBL6929311 0.83 DRD4 (0.38) NAMPTMAP4K4
Hydrochloric Acid SCHEMBL4669450 0.83 SAT1 (0.47) KCNH3SAT1NPC1RAB9A
SCHEMBL4962562 0.81 SAT1 (0.45) KCNH3SAT1NPC1RAB9ANAMPT
SCHEMBL30837752 0.79 CNR2 (0.33) KCNH3
SCHEMBL21744423 0.79 MAPT (0.38) KCNH3RAB9AALDH1A1NAMPTEPHX2
SCHEMBL1488097 0.78
SCHEMBL12066042 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7300953-B2 Process for preparing nitrile compound, carboxylic acid compound or carboxylic acid ester compound UBE INDUSTRIES, LTD (JP) 2007-11-27 US disclosed
US-20060287541-A1 Subjecting a 4-substituted tetrahydropyran-4-carboxylic acid compound to to decarboxylation in the presence of a metal catalyst for producing 4-substituted tetrahydropyran UBE INDUSTRIES, LTD. (JP) 2006-12-21 US disclosed
EP-1671937-A1 METHOD FOR PRODUCING NITRILE COMPOUND, CARBOXYLIC ACID COMPOUND OR CARBOXYLATE COMPOUND Ube Industries, Ltd. (JP) 2006-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060287541-A1 Subjecting a 4-substituted tetrahydropyran-4-carboxylic acid compound to to decarboxylation in the presence of a metal catalyst for producing 4-substituted tetrahydropyran CBR1, ALDH18A1, ME1 KCNH3 2293/4885SAT1 529/4885NPC1 3332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.