Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 6/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.41 |
| ▸ | KLK1 | P06870 | 3/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1867150 | 0.92 | MASP2 (0.43) | MASP2TACR1KLKB1KLK1 | |
| SCHEMBL1867894 | 0.92 | MASP2 (0.43) | MASP2TACR1KLKB1KLK1 | |
| SCHEMBL1866418 | 0.90 | CTSV (0.46) | MASP2TACR1KLKB1CTSL | |
| SCHEMBL1871181 | 0.90 | MASP2 (0.43) | MASP2TACR1KLKB1KLK1 | |
| SCHEMBL1874196 | 0.90 | MASP2 (0.43) | MASP2TACR1KLKB1KLK1 | |
| SCHEMBL1875013 | 0.90 | KLKB1 (0.44) | MASP2KLKB1KLK1 | |
| SCHEMBL1870902 | 0.89 | MASP2 (0.43) | MASP2TACR1KLKB1KLK1 | |
| SCHEMBL1861128 | 0.88 | MASP2 (0.44) | MASP2TACR1KLKB1KLK1CTSL | |
| SCHEMBL1867433 | 0.88 | MASP2 (0.42) | MASP2KLKB1KLK1 | |
| SCHEMBL1880431 | 0.87 | MASP2 (0.44) | MASP2TACR1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |