Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 3/20 | 0.39 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1867150 | 1.00 | MASP2 (0.43) | MASP2KLKB1LCKKLK1CYP51A1 | |
| SCHEMBL1875013 | 0.93 | KLKB1 (0.44) | MASP2KLKB1KLK1METTL3METTL14 | |
| SCHEMBL1870064 | 0.92 | MASP2 (0.42) | MASP2KLKB1KLK1TACR1 | |
| SCHEMBL1870902 | 0.92 | MASP2 (0.43) | MASP2KLKB1KLK1TACR1METTL3 | |
| SCHEMBL1866418 | 0.92 | CTSV (0.46) | MASP2KLKB1TACR1JAK2JAK1 | |
| SCHEMBL1871181 | 0.91 | MASP2 (0.43) | MASP2KLKB1KLK1TACR1 | |
| SCHEMBL1874196 | 0.91 | MASP2 (0.43) | MASP2KLKB1KLK1TACR1 | |
| SCHEMBL1867433 | 0.89 | MASP2 (0.42) | MASP2KLKB1KLK1JAK1 | |
| Trifluoroacetic Acid SCHEMBL1873249 | 0.89 | DPP4 (0.43) | MASP2KLKB1TACR1 | |
| SCHEMBL1861128 | 0.88 | MASP2 (0.44) | MASP2KLKB1KLK1TACR1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |