Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | ACSS2 | Q9NR19 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18711297 | 0.91 | RAB9A (0.42) | NPC1RAB9AACSS2SMN1; SMN2GAA | |
| SCHEMBL22198413 | 0.78 | NPC1 (0.35) | NPC1RAB9AACSS2 | |
| SCHEMBL20041705 | 0.77 | RAB9A (0.48) | NPC1RAB9AACSS2SMN1; SMN2ALDH1A1 | |
| SCHEMBL17507245 | 0.75 | NPC1 (0.51) | NPC1RAB9AACSS2SMN1; SMN2GAA | |
| SCHEMBL18711213 | 0.75 | ACSS2 (0.37) | ACSS2ALDH1A1CA1 | |
| SCHEMBL17507363 | 0.74 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL18711220 | 0.74 | KDM4E (0.45) | NPC1RAB9AACSS2SMN1; SMN2ALDH1A1 | |
| SCHEMBL18701299 | 0.74 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL17491659 | 0.73 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL20041633 | 0.72 | NPC1 (0.51) | NPC1RAB9AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200220085-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2020-07-09 | — | — | US | disclosed |
| US-20170098783-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2017-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170098783-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | EED, EML4, MT-ND4L | NPC1 4669/4885RAB9A 1859/4885ACSS2 4083/4885 |
| US-20200220085-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | EED, EML4, MT-ND4L | NPC1 4669/4885RAB9A 1859/4885ACSS2 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.