SCHEMBL18714367

SCHEMBL18714367

CC(C)CNC(=O)[C@@H](CCCCCNC(=O)OC(C)(C)C)ON1C(=O)c2ccccc2C1=O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TPSAB1 Q15661 3/20 0.44
TPSD1 Q9BZJ3 3/20 0.44
TPSG1 Q9NRR2 3/20 0.44
MALT1 Q9UDY8 1/20 0.42
KCNA5 P22460 1/20 0.41
BRD4 O60885 1/20 0.40
DRD2 P14416 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CXCR3 P49682 1/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
GAA P10253 1/20 0.38
ACE P12821 1/20 0.38
UTS2R Q9UKP6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13790038 0.99 TPSAB1 (0.43) TPSAB1TPSD1TPSG1MALT1KCNA5
SCHEMBL13790158 0.86 MEN1 (0.48) TPSAB1TPSD1TPSG1MALT1BRD4
SCHEMBL13765222 0.81 PTPRC (0.40) TPSAB1TPSD1TPSG1MALT1KCNA5
SCHEMBL13790112 0.78 PLA2G1B (0.39) NPSR1MEN1KMT2AKDM4EPOLB
SCHEMBL10463312 0.78 MALT1 (0.51) TPSAB1TPSD1TPSG1MALT1KCNA5
SCHEMBL13765035 0.77 ALDH1A1 (0.43) NPSR1MEN1KMT2AKDM4EPOLB
SCHEMBL17264137 0.76 TPSAB1 (0.53) TPSAB1TPSD1TPSG1MALT1BRD4
SCHEMBL5317930 0.76 MALT1 (0.47) TPSAB1TPSD1TPSG1MALT1KCNA5
SCHEMBL10463296 0.76 MALT1 (0.47) TPSAB1TPSD1TPSG1MALT1KCNA5
SCHEMBL8752938 0.74 TPSAB1 (0.51) TPSAB1TPSD1TPSG1MALT1BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9610263-B2 Method of modulating membrane potential of a cell VERSITECH LIMITED (CN) 2017-04-04 US disclosed