Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.38 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15757242 | 0.86 | PDE4B (0.41) | PDE4DPDE4APDE4BTRPC6PDE4C | |
| SCHEMBL18708222 | 0.86 | PDE4D (0.44) | CNR2PDE4DPDE4APDE4BTRPC6 | |
| SCHEMBL3633786 | 0.77 | TRPC6 (0.54) | CNR2PDE4DPDE4APDE4BTRPC6 | |
| SCHEMBL88281 | 0.75 | TRPC6 (0.49) | CNR2PDE4DPDE4APDE4BTRPC6 | |
| SCHEMBL18708221 | 0.75 | TRPC6 (0.49) | CNR2PDE4DPDE4APDE4BTRPC6 | |
| SCHEMBL71158 | 0.74 | TRPC6 (0.48) | CNR2PDE4DPDE4APDE4BTRPC6 | |
| SCHEMBL19444453 | 0.73 | CYP1A2 (0.33) | DHFR | |
| SCHEMBL20219434 | 0.73 | PDE4A (0.35) | PDE4DPDE4AERBB2EPHA2KDR | |
| SCHEMBL7148906 | 0.71 | PDE4B (0.42) | PDE4DPDE4APDE4BTRPC6DHFR | |
| SCHEMBL15669943 | 0.71 | CNR2 (0.38) | CNR2TRPC6DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611250-B2 | Process for preparing 4-(cyclopropylmethoxy)-N-(3,5-dichloro-1-oxido-4-pyridyl)-5-methoxypyridine-2-carboxamide | SANOFI (FR) | 2017-04-04 | — | — | US | disclosed |