Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15338931 | 0.92 | POLB (0.51) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL20807028 | 0.83 | POLB (0.53) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL16559838 | 0.81 | POLB (0.44) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL24440871 | 0.81 | POLB (0.43) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL20275161 | 0.80 | TDP1 (0.50) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL22845690 | 0.80 | POLB (0.41) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL20032595 | 0.80 | POLB (0.39) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL19803990 | 0.80 | TDP1 (0.43) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL26713016 | 0.80 | HTT (0.45) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL18486831 | 0.79 | POLB (0.40) | HTTPOLBAPEX1TDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617477-B2 | Compound having four polymerizable groups, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-04-11 | — | — | US | disclosed |