Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | CBX7 | O95931 | 2/20 | 0.46 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.46 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.46 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18722715 | 0.86 | MMP8 (0.41) | MMP8ALDH1A1MMP2MMP9CYP3A4 | |
| SCHEMBL17370968 | 0.84 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2USP2F2L3MBTL1 | |
| SCHEMBL18722718 | 0.84 | CBX7 (0.65) | MMP8ALDH1A1SMN1; SMN2USP2F2 | |
| SCHEMBL18722719 | 0.80 | MMP2 (0.51) | MMP8ALDH1A1SMN1; SMN2USP2F2 | |
| SCHEMBL18722717 | 0.78 | CBX7 (0.55) | MMP8ALDH1A1SMN1; SMN2USP2F2 | |
| SCHEMBL13284254 | 0.76 | F2 (0.64) | MMP8ALDH1A1SMN1; SMN2USP2F2 | |
| SCHEMBL28617622 | 0.75 | MMP8 (0.68) | MMP8ALDH1A1SMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL448167 | 0.74 | TSHR (0.47) | ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL27780980 | 0.73 | ALDH1A1 (0.47) | MMP8ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16377139 | 0.73 | ALDH1A1 (0.54) | MMP8ALDH1A1MMP2MMP9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9616047-B2 | Inhibitors of beta-catenin in treatment of colorectal cancer | REGENTS OF UNIVERSITY OF MINNESOTA (US) | 2017-04-11 | — | — | US | disclosed |