Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 11/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRND | Q07001 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318292 | 0.79 | CHRNA7 (0.32) | PLK1CSNK2A1PLK3METAP1CHRNA7 | |
| SCHEMBL3318336 | 0.72 | KDM4E (0.34) | KCNH2 | |
| SCHEMBL11280877 | 0.72 | CSNK2A1 (0.44) | PLK1CSNK2A1PLK3 | |
| SCHEMBL11270598 | 0.69 | PLK1 (0.41) | PLK1CSNK2A1PLK3 | |
| SCHEMBL18723490 | 0.69 | KDM4E (0.33) | KCNH2 | |
| SCHEMBL8327546 | 0.69 | HTT (0.41) | PLK1CSNK2A1PLK3ELANE | |
| SCHEMBL13415965 | 0.68 | BRD4 (0.44) | PLK1CSNK2A1PLK3ELANE | |
| SCHEMBL8221078 | 0.67 | L3MBTL1 (0.34) | — | |
| SCHEMBL1254852 | 0.66 | HPGD (0.39) | PLK1CSNK2A1PLK3 | |
| SCHEMBL2193115 | 0.65 | HTR1A (0.47) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066648-B1 | SUBSTITUTED DIMETHYLCYCLOBUTYL COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS | ESTEVE LABOR DR (ES) | 2017-04-12 | — | — | EP | disclosed |