Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216729 | 1.00 | EGLN3 (0.36) | EGLN3POLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8221078 | 0.78 | L3MBTL1 (0.34) | POLBALDH1A1KMT2A | |
| SCHEMBL3315410 | 0.76 | EGLN3 (0.31) | EGLN3POLB | |
| SCHEMBL23201120 | 0.67 | CYP19A1 (0.38) | EGLN3ALDH1A1 | |
| SCHEMBL18723738 | 0.66 | CYP1A2 (0.42) | POLBALDH1A1MAPT | |
| SCHEMBL3377520 | 0.66 | ADORA3 (0.32) | — | |
| SCHEMBL8218068 | 0.66 | BRD4 (0.35) | KMT2A | |
| SCHEMBL1430632 | 0.65 | CYP19A1 (0.38) | EGLN3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL18723481 | 0.64 | PLK1 (0.35) | — | |
| SCHEMBL3318958 | 0.64 | ADORA3 (0.32) | EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066648-B1 | SUBSTITUTED DIMETHYLCYCLOBUTYL COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS | ESTEVE LABOR DR (ES) | 2017-04-12 | — | — | EP | disclosed |