Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221078 | 0.87 | L3MBTL1 (0.34) | L3MBTL1HTTLMNAKMT2A | |
| SCHEMBL3995090 | 0.78 | CYP2D6 (0.33) | BRD4CREBBPL3MBTL1HTTLMNA | |
| SCHEMBL3318456 | 0.78 | CYP2D6 (0.33) | BRD4CREBBPL3MBTL1HTTLMNA | |
| SCHEMBL8221261 | 0.77 | TBXAS1 (0.35) | KMT2A | |
| SCHEMBL1456338 | 0.75 | HTT (0.41) | BRD4CREBBPHTTLMNA | |
| SCHEMBL31283708 | 0.71 | KDM1A (0.44) | L3MBTL1HTTLMNA | |
| SCHEMBL31682404 | 0.69 | HTT (0.41) | HTTLMNAKMT2A | |
| SCHEMBL8220817 | 0.69 | DRD2 (0.52) | — | |
| SCHEMBL8216729 | 0.66 | EGLN3 (0.36) | KMT2A | |
| SCHEMBL18723549 | 0.66 | EGLN3 (0.36) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008015266-A1 | SUBSTITUTED DIMETHYLCYCLOBUTYL COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2008-02-07 | — | — | WO | disclosed |