SCHEMBL1872509

SCHEMBL1872509

O=C(O)C(Cl)(Cl)CCCOc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
PPARA Q07869 2/20 0.44
TTR P02766 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C8 P10632 1/20 0.44
CHRM1 P11229 1/20 0.44
CYP2C9 P11712 1/20 0.44
ADRA1A P35348 1/20 0.44
PPARG P37231 1/20 0.44
HTR2B P41595 1/20 0.44
SLCO1B3 Q9NPD5 1/20 0.44
CISD1 Q9NZ45 1/20 0.44
SLCO1B1 Q9Y6L6 1/20 0.44
DHFR P00374 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 3/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11097422 0.82 PPARA (0.64) LMNATSHRTDP1SMN1; SMN2PPARA
SCHEMBL29381732 0.78 RAB9A (0.54) LMNATSHRTDP1SMN1; SMN2PPARG
SCHEMBL117098 0.78 RAB9A (0.54) LMNATSHRTDP1SMN1; SMN2PPARG
SCHEMBL5339875 0.75 LMNA (0.49) LMNATSHRTDP1PPARAPPARG
SCHEMBL6288400 0.74 LMNA (0.51) LMNATSHRTDP1PPARGDHFR
2,4,5-Trichlorophenoxyacetic Acid SCHEMBL11144266 0.73 TDP1 (0.56) LMNATSHRTDP1SMN1; SMN2L3MBTL1
Potassium Ion SCHEMBL1888583 0.70 LMNA (0.47) LMNATSHRTDP1SMN1; SMN2CYP1A2
SCHEMBL5335767 0.70 LMNA (0.47) LMNATSHRTDP1SMN1; SMN2HTR2B
SCHEMBL9065555 0.70 LMNA (0.47) LMNATSHRTDP1SMN1; SMN2CYP1A2
SCHEMBL93574 0.70 LMNA (0.47) LMNATSHRTDP1SMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US claimed
US-20090185867-A1 MARINE ANTI-FOULANT SYSTEM AND METHODS FOR USING SAME ASSET INTEGRITY MANAGEMENT SOLUTIONS, L.L.C., D/B/A AIMS INTERNATIONAL 2009-07-23 US claimed
EP-0449975-B1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1997-04-23 EP claimed
US-5441743-A In thermoplastic or thermosetting binder BATTELLE MEMORIAL INSTITUTE (US) 1995-08-15 US claimed
WO-1990006975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1990-06-28 WO claimed
US-10829636-B2 Antifouling composition BASF SE (DE) 2020-11-10 US disclosed
US-20180194941-A1 ANTIFOULING COMPOSITION BASF CORPORATION 2018-07-12 US disclosed
US-20180187008-A1 ANTIFOULING COMPOSITION BASF CORPORATION 2018-07-05 US disclosed
EP-3320009-A1 ANTIFOULING COMPOSITION BASF SE (DE) 2018-05-16 EP disclosed
EP-3320010-A1 ANTIFOULING COMPOSITION BASF SE (DE) 2018-05-16 EP disclosed
WO-2017007901-A1 ANTIFOULING COMPOSITION BASF SE (DE) 2017-01-12 WO disclosed
WO-2017007899-A1 ANTIFOULING COMPOSITION BASF SE (DE) 2017-01-12 WO disclosed
US-20090185867-A1 MARINE ANTI-FOULANT SYSTEM AND METHODS FOR USING SAME ASSET INTEGRITY MANAGEMENT SOLUTIONS, L.L.C., D/B/A AIMS INTERNATIONAL 2009-07-23 US disclosed
US-20080058211-A1 Method and Composition for the Modulation of Toxin Resistance in Plant Cells BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2008-03-06 US disclosed
US-20060265779-A1 Genetic and epigenetic manipulation of ABC transporters and ecto-phosphatases for the conference of drug resistance and for the loss of drug resistance in biological systems and methods for the detection of ecto-phosphatase inhibitors NATIONAL SCIENCE FOUNDATION 2006-11-23 US disclosed
US-5441743-A In thermoplastic or thermosetting binder BATTELLE MEMORIAL INSTITUTE (US) 1995-08-15 US disclosed
WO-1990006975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1990-06-28 WO disclosed
US-4029687-A HERBICIDES CIBA-GEIGY AG (CH) 1977-06-14 US disclosed
US-4004914-A HERBICIDES CIBA-GEIGY AG (CH) 1977-01-25 US disclosed
US-3962307-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed