Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001630 | 0.72 | TAS2R38 (0.46) | SMN1; SMN2TAS2R38NAPRTHSD17B10MEN1 | |
| SCHEMBL18725181 | 0.69 | TGM2 (0.42) | SMN1; SMN2TGM2CYP1A2TAS2R38HSD17B10 | |
| SCHEMBL9113008 | 0.67 | HTT (0.49) | SMN1; SMN2TAS2R38NAPRTHSD17B10MEN1 | |
| SCHEMBL20143330 | 0.67 | TGM2 (0.43) | SMN1; SMN2TGM2CYP1A2TAS2R38NAPRT | |
| SCHEMBL14868313 | 0.66 | TAS2R38 (0.45) | SMN1; SMN2TAS2R38NAPRTHSD17B10KMT2A | |
| SCHEMBL109209 | 0.63 | ALDH1A1 (0.43) | SMN1; SMN2TAS2R38NAPRTHSD17B10MEN1 | |
| SCHEMBL1792956 | 0.63 | ALDH1A1 (0.43) | SMN1; SMN2TAS2R38NAPRTHSD17B10MEN1 | |
| SCHEMBL14868330 | 0.62 | TAS2R38 (0.41) | SMN1; SMN2CYP1A2TAS2R38NAPRTHSD17B10 | |
| SCHEMBL9505592 | 0.62 | TAS2R38 (0.48) | SMN1; SMN2CYP1A2TAS2R38NAPRTHSD17B10 | |
| SCHEMBL19176502 | 0.61 | MAPT (0.53) | SMN1; SMN2TGM2CYP1A2TAS2R38NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156394-B1 | ALKYLIDENE AMINOGANIDINE AND SALT THEREOF, MODIFIER COMPOSITION, MODIFIED RUBBER FOR TIRE, RUBBER COMPOSITION FOR TIRE, AND TIRE | MITSUBISHI GAS CHEMICAL CO (JP) | 2019-04-17 | — | — | EP | disclosed |
| US-10173973-B2 | Alkylidene aminoguanidine and salt thereof, modifying composition, modified rubber for tire, rubber composition for tire, and tire | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2019-01-08 | — | — | US | disclosed |
| US-20170129850-A1 | ALKYLIDENE AMINOGUANIDINE AND SALT THEREOF, MODIFYING COMPOSITION, MODIFIED RUBBER FOR TIRE, RUBBER COMPOSITION FOR TIRE, AND TIRE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-05-11 | — | — | US | disclosed |
| EP-3156394-A1 | ALKYLIDENE AMINOGANIDINE AND SALT THEREOF, MODIFIER COMPOSITION, MODIFIED RUBBER FOR TIRE, RUBBER COMPOSITION FOR TIRE, AND TIRE | Mitsubishi Gas Chemical Company, Inc. (JP) | 2017-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129850-A1 | ALKYLIDENE AMINOGUANIDINE AND SALT THEREOF, MODIFYING COMPOSITION, MODIFIED RUBBER FOR TIRE, RUBBER COMPOSITION FOR TIRE, AND TIRE | TAAR1, PRMT9, RASGRP1 | SMN1; SMN2 589/4885TGM2 1255/4885CYP1A2 1588/4885 |
| US-10173973-B2 | Alkylidene aminoguanidine and salt thereof, modifying composition, modified rubber for tire, rubber composition for tire, and tire | TAAR1, PRMT9, RASGRP1 | SMN1; SMN2 589/4885TGM2 1255/4885CYP1A2 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.