SCHEMBL18729635

SCHEMBL18729635

CCc1cc(-c2ccccc2)ncc1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 2/20 0.54
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
PDGFRB P09619 1/20 0.45
KDR P35968 1/20 0.45
FLT3 P36888 1/20 0.45
CYP11B1 P15538 2/20 0.43
CYP11B2 P19099 2/20 0.43
KMT2A Q03164 2/20 0.41
CYP3A4 P08684 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
GSK3A P49840 2/20 0.39
GSK3B P49841 2/20 0.39
IDO1 P14902 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22548915 0.86 LDHA (0.42) LDHANPC1RAB9ASMN1; SMN2PDGFRB
SCHEMBL18729640 0.86 LDHA (0.58) LDHANPC1RAB9ASMN1; SMN2PDGFRB
SCHEMBL18729562 0.85 LDHA (0.49) LDHANPC1RAB9ASMN1; SMN2CYP11B1
SCHEMBL26382639 0.84 LDHA (0.43) LDHANPC1RAB9ASMN1; SMN2PDGFRB
SCHEMBL2188040 0.82 LDHA (0.46) LDHANPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL18730284 0.81 LDHA (0.46) LDHANPC1RAB9ASMN1; SMN2PDGFRB
SCHEMBL18730286 0.81 LDHA (0.46) LDHANPC1RAB9ASMN1; SMN2PDGFRB
SCHEMBL24851613 0.81 CYP1A2 (0.45) NPC1RAB9ASMN1; SMN2KMT2ACYP3A4
SCHEMBL13355974 0.80 LDHA (0.47) LDHANPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL18729551 0.79 LDHA (0.44) LDHANPC1RAB9ASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-11765966-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-11753425-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-12 US disclosed
US-11683981-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-20 US disclosed
US-11616203-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-03-28 US disclosed
US-20220359836-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-11-10 US disclosed
US-11139443-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-05 US disclosed
EP-3001480-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2017-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11616203-B2 Organic electroluminescent materials and devices ICOSLG, APOL1, OXA1L LDHA 37/4885NPC1 4092/4885RAB9A 740/4885
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, RO60, LIFR LDHA 242/4885NPC1 4672/4885RAB9A 560/4885
US-11139443-B2 Organic electroluminescent materials and devices ICOSLG, ORC3, OR10J3 LDHA 1654/4885NPC1 3005/4885RAB9A 1771/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 LDHA 192/4885NPC1 228/4885RAB9A 2081/4885
US-20220359836-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, EPM2A LDHA 14/4885NPC1 3768/4885RAB9A 1580/4885
US-11753425-B2 Organic electroluminescent materials and devices SSB, RO60, LIFR LDHA 242/4885NPC1 4672/4885RAB9A 560/4885
US-11683981-B2 Organic electroluminescent materials and devices OXER1, CHRM1, OSBPL8 LDHA 418/4885NPC1 1667/4885RAB9A 708/4885
US-11765966-B2 Organic electroluminescent materials and devices L1CAM, EPCAM, EPM2A LDHA 14/4885NPC1 3768/4885RAB9A 1580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.