SCHEMBL18729640

SCHEMBL18729640

CCc1cnc(-c2ccccc2)cc1C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 2/20 0.58
NOS3 P29474 1/20 0.50
NOS1 P29475 1/20 0.50
NOS2 P35228 1/20 0.50
RAB9A P51151 4/20 0.45
NPC1 O15118 4/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
PDGFRB P09619 1/20 0.45
KDR P35968 1/20 0.45
FLT3 P36888 1/20 0.45
KMT2A Q03164 2/20 0.43
CYP11B1 P15538 2/20 0.43
CYP11B2 P19099 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
PKM P14618 1/20 0.43
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15964137 0.86 LDHA (0.51) LDHANOS3NOS1NOS2RAB9A
SCHEMBL21888832 0.86 LDHA (0.46) LDHANOS3NOS1NOS2RAB9A
SCHEMBL26344805 0.86 NOS3 (0.50) LDHANOS3NOS1NOS2RAB9A
SCHEMBL18729635 0.86 LDHA (0.54) LDHARAB9ANPC1SMN1; SMN2PDGFRB
SCHEMBL18729562 0.85 LDHA (0.49) LDHARAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL24292237 0.84 LDHA (0.47) LDHANOS3NOS1NOS2RAB9A
SCHEMBL13355974 0.84 LDHA (0.47) LDHARAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL7203119 0.82 NOS3 (0.63) LDHANOS3NOS1NOS2
SCHEMBL18730297 0.81 LDHA (0.50) LDHARAB9ANPC1SMN1; SMN2PDGFRB
SCHEMBL18730751 0.81 LDHA (0.50) LDHARAB9ANPC1SMN1; SMN2PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844267-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-12 US disclosed
US-11839142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11778897-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-11744141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-11697662-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-11683981-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-20 US disclosed
US-20230010166-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-12 US disclosed
US-20220416179-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-29 US disclosed
US-11239434-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-01 US disclosed
US-11228004-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-01-18 US disclosed
US-11114624-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-09-07 US disclosed
US-20210002311-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-01-07 US disclosed
US-20190252627-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-15 US disclosed
EP-3159350-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-04-26 EP disclosed
EP-3001480-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2017-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (18 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MGLL, SELENOI, APOL1 LDHA 1714/4885NOS3 1404/4885NOS1 1822/4885
US-11844267-B2 Organic electroluminescent materials and devices L1CAM, LEF1, EPCAM LDHA 46/4885NOS3 3028/4885NOS1 1917/4885
US-11114624-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND LDHA 727/4885NOS3 2149/4885NOS1 1794/4885
US-11239434-B2 Organic electroluminescent materials and devices L1CAM, LEF1, EPCAM LDHA 13/4885NOS3 2842/4885NOS1 1383/4885
US-11228004-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG LDHA 352/4885NOS3 2888/4885NOS1 2766/4885
US-11778897-B2 Organic electroluminescent materials and devices LIFR, LBR, ZFR LDHA 1004/4885NOS3 1715/4885NOS1 2592/4885
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 LDHA 273/4885NOS3 1243/4885NOS1 903/4885
US-20190252627-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, LEF1, EPCAM LDHA 13/4885NOS3 2842/4885NOS1 1383/4885
US-20210002311-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC LDHA 539/4885NOS3 1755/4885NOS1 1374/4885
US-20220416179-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, LEF1, EPCAM LDHA 48/4885NOS3 2481/4885NOS1 1379/4885
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR LDHA 639/4885NOS3 1165/4885NOS1 1290/4885
US-11744141-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, LBR LDHA 144/4885NOS3 3629/4885NOS1 3215/4885
US-20230010166-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, CHRM1, OSBPL8 LDHA 418/4885NOS3 2746/4885NOS1 1195/4885
US-11683981-B2 Organic electroluminescent materials and devices OXER1, CHRM1, OSBPL8 LDHA 418/4885NOS3 2746/4885NOS1 1195/4885
US-11697662-B2 Organic electroluminescent materials and devices LIFR, C1R, LBR LDHA 700/4885NOS3 1198/4885NOS1 1083/4885
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, ZFR LDHA 1004/4885NOS3 1715/4885NOS1 2592/4885
US-11839142-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP LDHA 318/4885NOS3 1931/4885NOS1 710/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 LDHA 1161/4885NOS3 2364/4885NOS1 3055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.