Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120281 | 0.91 | GAA (0.49) | GAAALDH1A1CCR1HPGDLMNA | |
| SCHEMBL1119911 | 0.84 | FAAH (0.34) | IRAK4ALDH1A1CCR1 | |
| SCHEMBL1120023 | 0.81 | ALDH1A1 (0.34) | GAAIRAK4ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL18978946 | 0.80 | GAA (0.37) | GAAALDH1A1KMT2ASMN1; SMN2CCR1 | |
| SCHEMBL19053589 | 0.79 | GAA (0.37) | GAAIRAK4ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL1120082 | 0.79 | GAA (0.47) | GAAALDH1A1SMN1; SMN2CCR1HPGD | |
| SCHEMBL1758419 | 0.78 | GAA (0.49) | GAAALDH1A1CCR1LMNA | |
| SCHEMBL1120293 | 0.77 | GAA (0.49) | GAAALDH1A1CCR1HPGDLMNA | |
| SCHEMBL19053594 | 0.76 | GAA (0.35) | GAAALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL2509441 | 0.76 | GAA (0.50) | GAACCR1HPGDLMNASPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150237859-A1 | Thiazol-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-27 | — | — | US | disclosed |
| US-9029549-B2 | Thiazol-4-carboxylic acid esters and thioesters as plant protection agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-20140031553-A1 | Thiazol-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| US-8569509-B2 | Thiazole-4-carboxylic acid esters and thioesters as plant protection agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-29 | — | — | US | disclosed |
| EP-2280965-B1 | THIAZOL-4-CARBOXYLIC ACID ESTERS AND THIOESTERS AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2012-08-29 | — | — | EP | disclosed |
| US-20110105429-A1 | Thiazole-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | US | disclosed |
| WO-2009132785-A1 | THIAZOL-4-CARBOXYLIC ACID ESTERS AND THIOESTERS AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2009-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031553-A1 | Thiazol-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | LYPLA1, ACOT7, PPT1 | GAA 410/4885IRAK4 888/4885ALDH1A1 436/4885 |
| US-20110105429-A1 | Thiazole-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | ACOT7, LYPLA1, PPT1 | GAA 502/4885IRAK4 892/4885ALDH1A1 459/4885 |
| US-20150237859-A1 | Thiazol-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | LYPLA1, ACOT7, PPT1 | GAA 410/4885IRAK4 888/4885ALDH1A1 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.